BCMETDB was created as an online resource, functioning as a database that offers
extensive information on different modifications such as acetylation, methylation, etc., specifically related
to mRNAs and their associated pathways, as well as non-coding RNAs (including miRNAs, long non-coding RNAs,
circular RNAs), and small compounds. Both coding RNAs (which serve as biomarkers) and non-coding RNAs play a
crucial role in regulating various cascades involved in the metastasis of breast cancer. Our database comprises
a compilation of comprehensive and regularly updated information derived from literature research and other
databases. Each entry in the database is categorized based on the type of RNA it involves, along with its
respective mechanism, impact on metastasis, and reference source. Additionally, BCMETDB provides details on
RNA mutations, mRNA pathways, reactome, gene cards, and gene information.
Furthermore, users have the option to submit their own data through the user portal by completing the relevant form. The submitted data will be verified and subsequently added to the database by the administrator. Users will receive notifications regarding the status of their submissions. The database establishes cause-and-effect relationships by presenting experimentally verified mRNAs, along with various physiological modifications, dysregulation of associated pathways, and interactions with non-coding RNAs that are specifically identified in breast cancer metastasis. We anticipate that BCMetDB will serve as a valuable resource for the breast cancer metastasis research community.
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